Showing posts with label RNA interference. Show all posts
Showing posts with label RNA interference. Show all posts

Monday, July 20, 2020

How is Artic Apple so clear in the inside?

Genetically Modified Non-Browning Apples Are Approved in the U.S. ...



    As we learn more and more about what genes work and what doesn't. It's always  exciting and fun to use gene to satisfying our taste buds desires. It's always annoying eating an apple only to bite into it having browning developing, or wishing you can have more bite out of your apple. The solution of your desire have been solved. Scientist have developed a apple that does not brown, and was recently approved by the FDA and USDA as safe for consumption. I know your thinking how? Scientist and researchers have being working on a way to stop the development of browning of apples decades.
     There is polyphneol oxidase enzyme(PPO), which is released inside the structure of the apple that interacts with the polyphenols and oxygen, this is the cause of the browning. The PPO and the polyphenols are usually separated but mishandling of the apple(throwing,crushed, or drop) causes the interaction between the three. To combat this, scientist developed an anti-PPO gene, they used RNA interference to destroy specific RNA structures that produced the PPO. Now we have an apple that can be tossed, crushed, or accidental dropped,and still be perfectly clear in the inside.







Tuesday, April 30, 2019

The Only Bad Thing About Summer

An article was published by Science Daily, which summarizes a research study where a discovery was made which could save thousands of lives. The study was conducted by a team of researchers from the University of Arizona led by Jun Isoe. The report was published in PLoS Biology January 8th 2019. During this study, the researchers searched for genes which were exclusive to mosquitoes. To execute this task they utilized a technique known as bioinformatics. Through this process they discovered proteins which were unique to only mosquitoes. This was a crucial discovery due to the current pesticides on the market being non specific and killing off beneficial insects such as honey bees. 40 proteins were discovered, however only one contained the capability of effecting reproduction. They named this protein Eggshell Organizing Factor 1 (EOF-1). The name stemmed from its function during eggshell synthesis. RNA interference was used as a means of inhibiting this protein function which led to a unsuccessful eggshell formation resulting in death of the embryo. After further testing it was confirmed that the creation of a drug which targets EOF-1, would be an effective pesticide which could prevent the occurrence of diseases spread by mosquitoes.
It is safe to say we all hate mosquitoes. Unlike virtually any other insect, there are no friends lovers of mosquitoes. However, there is information which could pursued one to not wish to completely eradicate them. Although pests and even deadly to humans, certain plants and animals utilize mosquitoes for survival. That being said, I believe funding and research should be increased in this area especially for the purpose of eliminating the mosquitoes which are vectors for disease.