Showing posts with label SEZ6L gene. Show all posts
Showing posts with label SEZ6L gene. Show all posts

Wednesday, November 16, 2016

Beagles Linked with Human Gene Deficiency

In this article, researchers found that DNA in beagles are linked to social disorders in people. There are five genes in a beagle, which are linked to their social behavior. Four out of the five genes have been found in humans who has social disabilities such as schizophrenia, autism, and aggression. A specific gene, SEZ6L, was the specific gene observed when researching the beagles. What researchers found was that even though in humans these genes make them socially awkward, it is actually beneficial for the beagles.

The researchers performed an experiment. There were three different treats under three glass plates. (One under each plate). The last plate was screwed in, making it impossible for the dog to get. The dog at first thought getting the treats was easy, considering the first two treats were eaten within seconds of trying to get them. It seemed that when the beagle tried to get the third treat and could not, he looked to the human in the room for help. Showing some social skills other animals such as wolves would not show. Some researchers are unsure of how accurate this in only because the experiment was done in beagles and not other dog breeds. Further experiments with different breeds should be done. Here is more about the experiment.

I found this article so interesting because it reminds me of my dog. Trooper, my dog, is very social. When he needs me, he lets me know. He constantly brings his ball to me, puts it on my lap and makes these noises until I do something about it. It is not a cry and it is not a bark, its like he is trying to tell me what to do. He does this anytime he needs something and its actually very convenient. On the other hand, my two other dogs are not so vocal. It makes me wonder if these are coincidences or if there is a gene only in specific breeds.


Sunday, October 2, 2016

The Genes Behind Why Dogs are Man's Best Friend

   
 “Dogs are man’s best friend” is a very common quote used to describe the fondness and loyalty dogs have for humans. Surprisingly, research shows that the same genes linked to social disorders in humans, such as autism, are possibly the same genes behind dogs’ social behavior towards humans.


The behavioral experiment in which dogs’ sociability towards humans was tested.


    A behavioral experiment was conducted using hundreds of lab-bred beagles, in which they were given a task to open three transparent lids containing treats, one of them being tightly closed. The dogs were observed to seek help from the person standing in the room after finding it hard to open that lid, instead of finding a way to open it on their own. Some of them looked at the observer and then back at the stuck lid, while others tried to make physical contact or stayed close to the observer. The Gender of the beagles was also shown to play a role, in which females were shown to be more sociable than males.

    A DNA testing method, called Genome-Wide Associated Studies (GWAS), was used to study a large number of variants within each dog’s genome. Results showed that five genes selected during domestication were heavily linked to dogs’ sociability towards humans. Four of these genes, including the SEZ6L gene, have also been linked to human social disorders, such as autism, schizophrenia, aggression, and ADHD. The evidence however, is not enough to prove this correlation, since this test was only performed on beagles. Scientists plan to do further research on other dog breeds, and hope that this information would also be useful in gaining a better understanding of human social disorders.

    I found this information very fascinating because I never knew that a gene that can possibly be beneficial in one species, can be harmful in another. I’m looking forward to reading more about this when further research and confirmation are made.


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