Monday, October 9, 2017
Researchers from Switzerland has done a study on TORC1, which is an enzyme that controls the normal cell growth in the body. When this enzyme is too active it causes diseases such as cancer. The Target Of Rapamycin (TOR) was first discovered in yeast, and then in humans. TOR is found in two very different proteins, TORC1 and TORC2. Researchers from UNIGE, the University of Auckland, New Zealand, and the École Polytechnique Fédérale de Lausanne (EPFL) collaborated to understand how the nutrient regulates the activity of TROC1. The researchers were able to reveal the appearance of a new TORC1 structure in cells. When the cells lack glucose, the TORC1 assemble together forming a tubular structure. The tubular structure which is the TOROID, stores inactive TORC1 and stops cell growth. Another study done by National Centre of Competence in Research (NCCR) showed that the re-addition of glucose causes the TORIDS or the tubular structure to rapidly dissemble. NCCR has done the testing in yeast. The assembly and disassembly of the TOROIDS will make it possible to search for compounds that can stabilize and destabilize the cells. This article was very interesting to me because it could lead to curing cancer. If the cancer cells could be stopped from growing, millions of lives would be saved. Its amazing to see how modern technology can change cells from being able to grow. This research could open up new approaches to treat many diseases and change the world for ever.