Depression is a serious medical illness that is described as feeling sad, blue, and miserable. Most of this feel this for a short period. Clinical depression, or known as major depression disorder affect how one feels, thinks, and behaves that causes emotional and physical issues. Depression requires a long term treatment that can be treated with medicine or psychological counseling. There are a variety of factors that causes depression such as biological differences- people have physical changes in their brain, brain chemistry- neurotransmitters out of control chemicals controls depression, Inherited traits- depression is more common who have relatives with these condition, life events, or hormones. According to health line, “A person with a relative who suffers from depression is almost five times more likely to develop depression as well”. Research has found a gene in multiple family members with depression. Scientist have found that about 40% of the people who have depression has a genetic link. People with depressed parents are siblings are three times more likely to have the condition. For this reason, it strongly suggest that it is an inherited illness. Studies have also found that women are about 15% more likely for the chance of hereditary depression compared to men. Many researchers have found that a combination of genes leads to the depression disorder. 
Most of study on genetic depression is based on identical twins since they have the same exact genetic code. It was found that when one identical twin gets depressed, the other twin will 80% most likely get depressed. It is concluded that there’s a strong genetic influence since both twins become depressed at a high rate. Fraternal twins who share 50% of the genes do not have a high connection in depression. When one fraternal twin gets depressed, there’s only a 20% chance the other twin will also get depressed.
Main Link: http://www.healthline.com/health/depression/genetic#OtherFactors3
Related Link:http://depressiongenetics.stanford.edu/mddandgenes.html
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