Genetics Prevent Heart Attacks

Cardiovascular disease have a variety of problems associated with blood vessels and arteries within the heart. It is a condition that involves a blockage or narrowing of the blood vessels that can lead into a heart attack, stroke, and much more. Heart diseases are the most common and the leading cause of death in the United States. This led scientists on a investigation on how they can prevent heart problems and other human diseases. The Washington University School of Medicine performed and studied two genes that protects specific heart diseases. Researchers collected DNA from patients with coronary heart disease and from the healthy control group. They found genetic variation among the 220,000 patients and alternated the proteins that influenced the risks of coronary heart diseases. ANGPTL4 and SVEP1  were the two genes that were implicated and responsible for reducing the risks of coronory heart disease. Errors during DNA replication, ANGPTL4 and SVEP1 are the key genes relavent to cornory heart disease. Through cutting and alternating the DNA proteints the chances for coronary heart disease was reduced 50 percent. Although, SVEP1 has an oppostie role it actually increases the risks of coronary heart disease by 14 percent when the protein is alternated. This indicates that research needs to be done for understanding the genetic errors associated with cardiovascular diseases.

Through this research, it confirms that the newly identified genes linked with coronary heart diseases shows a big advantage for preventing heart problems and provide better drugs as well. New insights for discovering the implications between the ANGPTL4 and the SVEP1 may help find better treatments and a earlier onset for doctors to treat heart patients. Scientists using genetic studies to identify the biological pathways for human diseases is a great method for providing more genetic information for other human diseases.

Genetic Errors Linked To Life-Threatening Pregnancy Disorder

Scientists have identified genetic errors in women with autoimmune diseases that increase the risk of preeclampsia, a potentially life-threatening condition that occurs in 10 percent of all pregnancies.
The researchers also found the same mutations in some women with preeclampsia who don't have underlying autoimmune diseases. Their findings provide genetic targets for new treatments and suggest that screening tests could one day identify women at risk of the condition, which accounts for fifteen percent of all preterm births.

Preeclampsia typically develops after the 20th week of pregnancy. It causes dangerously high blood pressure, protein in the urine, headaches and swelling of a mother's hands and face. The only treatment is to induce delivery, which can be fatal to the baby if preeclampsia strikes too early in pregnancy.Preeclampsia results from a breakdown of the placenta, which delivers oxygen and nutrients to the baby. If the condition is not treated, preeclampsia can lead to seizures, strokes, kidney and liver damage and breathing problems that threaten the lives of both mother and baby.

In a recent study, 250 women with lupus and/or with  similar conditions.  Out of 250, forty women either developed preeclampsia, or suffered from it from previous pregnancies.  Also, researchers found that in these forty women, at seven of them had mutations for three genes that code for your immune system's response for injury and infection.

I think this could be a genetic break through.  Finding out the gene for this condition, and some how mutating it in a way so that the fetus will not carry it would be amazing.  This can lead to deleting genes for other disorders as well.