Cardiovascular disease have a variety of problems associated with blood vessels and arteries within the heart. It is a condition that involves a blockage or narrowing of the blood vessels that can lead into a heart attack, stroke, and much more. Heart diseases are the most common and the leading cause of death in the United States. This led scientists on a investigation on how they can prevent heart problems and other human diseases. The Washington University School of Medicine performed and studied two genes that protects specific heart diseases. Researchers collected DNA from patients with coronary heart disease and from the healthy control group. They found genetic variation among the 220,000 patients and alternated the proteins that influenced the risks of coronary heart diseases. ANGPTL4 and SVEP1 were the two genes that were implicated and responsible for reducing the risks of coronory heart disease. Errors during DNA replication, ANGPTL4 and SVEP1 are the key genes relavent to cornory heart disease. Through cutting and alternating the DNA proteints the chances for coronary heart disease was reduced 50 percent. Although, SVEP1 has an oppostie role it actually increases the risks of coronary heart disease by 14 percent when the protein is alternated. This indicates that research needs to be done for understanding the genetic errors associated with cardiovascular diseases.
Through this research, it confirms that the newly identified genes linked with coronary heart diseases shows a big advantage for preventing heart problems and provide better drugs as well. New insights for discovering the implications between the ANGPTL4 and the SVEP1 may help find better treatments and a earlier onset for doctors to treat heart patients. Scientists using genetic studies to identify the biological pathways for human diseases is a great method for providing more genetic information for other human diseases.
This is a great discovery for people with heart disease. As the number of people with heart problem increases, genetic studies like this will be very useful. It will open new pathways for understanding heart disease and curing it. Although, further studies are needed, alternating protein to reduce the chances of coronary heart disease is still a advantage for curing the disease.
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