Can your genetic history increase your chances of acne?

    When teenagers go through puberty it is not uncommon for acne to be appear. During these changing times, your body is under a lot of stress and pressure to mature for adulthood. Acne has levels of severity, but when sebaceous glands get clogged and become swollen which can create lesions through the skin is when acne can be considered a disorder. There are not exact causes of acne as everyone is their own individual, but some suggestions are; diet, stress, medications, hormones and even genetics.

    Teenagers that develop acne usually have parents or another family member that had acne as well. Based on a study of adolescent twins approximately 50%-90% of acne was caused by genetic variation. Another important finding from the study showed that up to 47% of at least one twin had acne. It is believed that the G-variant in the MYC region has an influence on acne, breast and prostate cancer.

    There are many studies being conducted in order to define more exact causes of acne. This way there can be preventative measures taken in order to satisfy patients who may develop acne later on. Although everyone is unique to one another, it can be inferred that if acne or skin disorders are common in your family, there is the risk of having it as well. 

Immune pathway shows benzoyl peroxide absolves acne

 

Abigail Eisenstadt discovered that benzoyl peroxide is able to squalene's effect on immune cells that are attacking acne bacteria. A relationship between the  immune system and acne was observed by RNA sequencing and Modlin and colleagues macrophages, or white blood cells, which rush to sites of infection to engulf intruders. Macrophages use oxidation to kill bacteria on the skin. Since the benzoyl peroxide is an oxidizing chemical, it can be harnessed to kill acne-causing bacteria when natural macrophages cannot. Finally the a renounced dermatologist recognizes benzoyl peroxide's ability to reduce redness and combat acne. 

I find this information very useful for younger individuals that are battling acne and the side effects it causes. Many teenagers going through puberty struggle with acne and do no know the most effective way to combat it is. In addition, it is important to know what is scientifically proven and was is used as marketing for consumption. 

Adult Acne and Genetics

Have you ever thought about why some people have acne and others do not? It may be because of genetics. In a small number of individuals, acne continues into adult hood. Researchers conducted a study with 1,203 first-degree relatives of 204 adult acne cases. They also had a control group of 856 first-degree relatives of 144 non-acne volunteers. From the study, they concluded that people with adult acne had far more relatives with adult acne than those that were unaffected. Another study was done involving 458 pairs of monozygotic twins and 1,099 pairs of dizygotic twins. They found that 81% of twins with adult acne had a family history of it and 19% had adult acne due to environmental factors. 400 twins with acne had significantly low levels of apolipoprotein A1 when compared to 2,414 unaffected twins. This was the only found trait that all affected individuals shared. No other factors contributed to adult acne, only genetic susceptibility.

I have seen it to be common in people in my family to have adult acne. It seems to "run" in the family. This may be because of genetics!

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