Showing posts with label Computer science. Show all posts
Showing posts with label Computer science. Show all posts

Tuesday, April 12, 2016

DNA Data Storage






A recently published article in the New York Times discusses new research involving computer data storage.  Two recent experiments involving teams from the University of Washington and Microsoft, as well as a separate group at the University of Illinois, have shown that DNA molecules can be the basis of an archival storage system.  This system could potentially have the capability of storing all the world's digital information in only nine liters of a solution!  This new technology would allow retrieval of specific digital files in an immense amount of data.  This vast amount of information has the potential to last for thousands of years.  This length of time is a huge benefit in comparison to current microelectronic data systems because they can only store data safely for several decades.  This storage capacity will be essential to keep up with the exponential growth of digital storage needs in the technological age.
 The raw data storage capabilities of this technology are incredible and are completely unfeasible even with the most advanced electronic magnetic storage systems. The researchers theorize that DNA could store up to an exabyte of data in the volume of a grain of sand. Douglas M Carmean, a researcher from Microsoft said, "In the last year, it suddenly hit us that this fusion of  computer technology and biology will be where future advances come from." The ingeniousness of DNA data storage is that scientists exploit the self-assembly nature of DNA replication, essential for life in living organisms.
The scientists admit that there are technological advancements that must occur in order to write the information in DNA, but they say that the technology is improving quickly.  A current issue with the technology is that data retrieval is "snaillike" in comparison with magnetic storage.  In addition, the technology is still very expensive but Dr. Leproust says, "The cost of digital information in DNA will soon come down by several orders of magnitude." This new research is an exciting biotechnological advancement and almost sounds like something out of a science fiction movie.  The research is still new and there still needs to be further technological advancements but if Moore's law holds true then DNA data storage will be commonplace in the future.  This type of research is exciting and makes me appreciate how quickly the genetics field has progressed.

Thursday, December 4, 2014

Computer can now model complex 3D shapes with hopes for DNA

Researchers reveal they have created a computer which they claim can now model intricate 3D shapes such as rings, bowls, and icosahedrons which are related to structures of viruses. The hopes of the newly developed technology is the branching of the computer to be used for DNA. So far DNA has been observed an analyzed by its sequences of its nucleotide building blocks, but another important property of DNA is its shape. About ten years ago scientists began manipulating DNA in 2D beginning "DNA Origami." As nanotechnology improved the scientists progressed towards 3D manipulation. The 3D nanostructures are utilized for the hope of creating methods to deliver drugs more effectively, enhance RNA Therapies, and cause artifical photosynthesis from chromophores.

The latest version of a model named CanDo cuts DNA sequences into subunits called "multiway junctions" which is what normally allows DNA strands to cross over during replication. The computer model reassembles the multiway junctions into the nanoscale shapes. Professor Bathe (MIT) reveals that the DNA shapes are "passive scaffolds" as their function would come from other molecules attached to them. 


I found this article interesting because I feel this is a big step for geneticists and those who study anything that is extremely small. A computer which can model structures for these researchers will bring a lot more understanding and success for those who use it.Also, how the researchers at MIT are using it displays the capability for the computer to be used for the medical field to help understand and hopefully improve the methods used by medical staff to treat patients.