Computer can now model complex 3D shapes with hopes for DNA
Researchers reveal they have created a computer which they claim can now model intricate 3D shapes such as rings, bowls, and icosahedrons which are related to structures of viruses. The hopes of the newly developed technology is the branching of the computer to be used for DNA. So far DNA has been observed an analyzed by its sequences of its nucleotide building blocks, but another important property of DNA is its shape. About ten years ago scientists began manipulating DNA in 2D beginning "DNA Origami." As nanotechnology improved the scientists progressed towards 3D manipulation. The 3D nanostructures are utilized for the hope of creating methods to deliver drugs more effectively, enhance RNA Therapies, and cause artifical photosynthesis from chromophores.
The latest version of a model named CanDo cuts DNA sequences into subunits called "multiway junctions" which is what normally allows DNA strands to cross over during replication. The computer model reassembles the multiway junctions into the nanoscale shapes. Professor Bathe (MIT) reveals that the DNA shapes are "passive scaffolds" as their function would come from other molecules attached to them.
I found this article interesting because I feel this is a big step for geneticists and those who study anything that is extremely small. A computer which can model structures for these researchers will bring a lot more understanding and success for those who use it.Also, how the researchers at MIT are using it displays the capability for the computer to be used for the medical field to help understand and hopefully improve the methods used by medical staff to treat patients.
I think this is a HUGE advancement for the genetics field, because a lot of diseases have to do with our DNA and now it will be easier to observe and possibly find out where diseases originate from.
ReplyDeleteThis is an amazing advancement and it's interesting because it'll combine the technologies from different fields in order to better see the structure of something small and complex, such as DNA.
ReplyDeleteThis advancement in technology is huge for not only doctors and specialists but also hospital workers, and even patients who can gain a better understanding of what is going on in their bodies. This technology will lead to far more discoveries and is for sure the future of medicine.
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