Showing posts with label faconi anemia. Show all posts
Showing posts with label faconi anemia. Show all posts

Thursday, December 4, 2014

Red Wine can cause cancer… and help prevent cancer?

Alcohol has been known to be a cause of cancer in the neck and head.  The relationship of alcohol and cancer became more prominent after the study of Faconi anemia.  Faconi anemia is a disease affecting 1 in 350,000 babies and is characterized by the inability to repair tangles of DNA known as “crosslinks.”  Cancer caused by Facoin anemia and alcohol-caused cancer, share the same mechanism of partially metabolized alcohol.  When alcohol is metabolized, it is converted into acetyl aldehyde before being converted to aldehyde dehydrogenase.  Acetyl aldehyde is a carcinogen and produces DNA cross links.  Though acetyl aldehyde is converted into aldehyde dehydrogenase, it still affects the body.  Because red wine is an alcohol, it has the potential to cause cancer.


While red wine has the potential to cause cancer, it is reported to have the fewest incidences of alcohol-caused cancer.  According to Robert Sclafani (PhD, investigator at the University of Colorado Cancer Center), red wine is able to block the cancer-causing effect of alcohol.  The reason red wine is able to block the effects is due to resveratrol, which is found in grape skins and eliminates cells with DNA damage.  In short alcohol can damage cells, giving them the potential to become cancerous, and resveratrol removes damaged cells.   However, if an individual was to still drink in excess it will still cause cancer.



I think the most interesting part of this article, is not the irony of red wine, but the potential of resveratrol.  It not only can help with killing potential cancer cells, it also has the ability to prevent damage to blood vessels, reduces low-density lipoprotein cholesterol and prevents blood clots.  I think it will be very interesting to see what medical professionals and scientist create with resveratrol and how it will help with cancer in the future.