Showing posts with label DNA amplification. Show all posts
Showing posts with label DNA amplification. Show all posts

Saturday, July 25, 2020

Ancient Scrolls having genes?

Dead Sea Scrolls
Researcher have figured out a way to extract tiny amounts of ancient DNA from scrolls. This is an extraordinary finding on how they did it and what they discovered. The researchers were able to extract DNA from a scroll that was made with animal skin."In research conducted over the past seven years, an interdisciplinary team from Tel Aviv University, the Israel Antiquities Authority (IAA), Sweden’s Uppsala University and Cornell University decoded the ancient DNA from the animal skins on which the scrolls were written. They were able to accurately determine the genetic relationships between various fragments, which could have far-reaching implications for the wider historical context of the scrolls"[2]



It's amazing to see and understand how they were able to extract DNA from the different fragments of the scroll to figure out that it was sheep and cow hide. They used a technique called Deep-sequencing technology, which was used to amplify animal DNA to compare to fingerprints of animal they had in they're data base. They were then able to pin point, which area the cow and sheep originated from to get an idea where the scroll was created. This is a huge accomplishment because there can do this with me written scrolls, to pinpoint where it was created.

 

Monday, November 16, 2015

Forensic Evidence Poses a Threat to the Innocent

Cynthia M. Cale argues that "touch DNA" could be causing issues in current forensic analysis. Research has been conducted at the University of Indianapolis proving that it is quite easy for someone's DNA to be transferred to a crime scene without the person being there at all. It is now possible for genetic profiles to be made from merely a few skin cells left, but these genetic profiles prove to be inaccurate.

In a courtroom, "touch DNA" is assumed to be left somewhere from direct contact, but studies are showing that there is no way to know whether or not it was from direct contact or secondary contact. It is possible that after shaking someone's hand, that person could deposit your DNA somewhere else, unknowingly. Because DNA amplification kits have become so sensitive and advanced, a forensic analyst only needs as few as 100 pico grams of DNA to create a genetic profile.

In 2013, Lukis Anderson was charged with murder because his DNA was found under the fingernails of the victim. At the time of the murder, he was in the hospital and the same paramedics took him there that transported the victim. The paramedics transferred Anderson's DNA to the victim most likely. An experiment was carried out by having a pair shake hands for two minutes and then held separate knives, In 85% of the cases, the DNA of the partner was transferred to the knife, and in 20% of the cases the other person was identified as the main contributor of DNA to the knife. This means that it is a very real possibility that this happens in the real world,

With the advancement of technology all the time, this could pose a very big issue. This secondary transfer of DNA could possibly wrongfully convict an innocent person just because they came in contact with someone else. In the courts, the jury is just told that there is a 1 in a quadrillion chance it's not the defendant, but they don't know the process behind it. This definitely needs to be addressed in certain cases of using "touch DNA" as the evidence in a case.