The loss of Y chromosome causes an increased risk of heart disease. A study was done on male mice who were genetically engineered to lose their Y chromosome. It was shown that when these mice no longer had the Y chromosome in their blood, scar tissue began to build up in their heart which led to heart failure. There have been studies in the past done by Dr. Walsh about how losing the Y chromosome causes different medical conditions in males. He still was trying to find out what caused this, so he continued his study on the mice, which showed a direct cause and effect relationship with heart, kidney, and lung disease. This can also be the cause of shorter life span for men. It was concluded that the loss of Y was due to cell division and eventually disintegration of Y chromosome in the blood.
This study is important because heart disease is one of the leading causes of death. If they can pinpoint where this issue is coming from then they can research solutions. This was very interesting because I did not know this could be a major cause of heart disease. Overall this was a good article and very informative.