Recent studies have shown that there are numerous genetic variants that are involved in determining the age of the onset of menopause. People who are born with ovaries have a set number of oocytes that will either mature into eggs or be destroyed if they contain damaged DNA. As these people get older, the number of these cells continues to decrease until this store of eggs is completely gone and menopause sets in. Researchers have found 290 different variants that determine when that store of eggs will become depleted. The biggest gene to affect this is CHEK2, which can delay menopause for a few years by affecting the CHEK2 protein. Researchers are looking into how they can target this gene in order to help women who want to have kids later in life. This study has only been done in mice so far but one day they hope to be able to see it in humans.