The researchers bred mice to lack a microbiome and transplanted bacteria from autistic patients to one group of these mice. As they observed the mice, they noted that they began to show similar signs and symptoms of autism in humans. In addition, the brains of the mice altered in gene expressions. There were two metabolites that were lower in mice with the microbiota which affect GABA receptors in the brain.
Arizona State University noted that individuals with autism often have gastrointestinal problems more frequently than those without autism. Scientists explored microbiota transfer therapy for autistic children in order to resolve their gastrointestinal problems and see if it affected other markers of autism. In their study, 58% of the children’s gastrointestinal problems improved and 48% showed improved autism symptoms.
Microbiota transfer therapy showed to be successful over a 2-year period study but is seen as unethical to whether autism has symptoms or is neurodiversity. Autism is known to negatively and s everely impact the daily life of an individual with the disorder. For scientists to transfer gut bacteria in patients with autism to improve their symptoms is an amazing discovery and treatment option. There are more beneficial outcomes to this therapy than there are disadvantageous, therefore should be available to those who could improve from it.