Saturday, April 14, 2018

How intestinal bacteria can affect your blood sugar and lipid levels

Researchers at the Kumamoto University lead a further discovery into the mechanism of the intestinal bacteria and its influence on sugar and lipid metabolism as that could shed some light on the metabolic diseases that affect the world today, like diabetes and dyslipidemia. The amount and possibly the profile of the intestinal bacteria seems to differ from person to person, especially when regarding weight. This variation in bacterial bacteria could overall affect the daily routines of the person, in terms of energy and fat accumulation in the body. This bacteria is known to be present in the very common Type 2 Diabetes, which further pushes the idea that there could be further research done to analyze the bacteria so to get insight on a possible way to prevent or help Type 2 Diabetes victims.
The researchers then conducted two types of experiments using two mouse models, one group being antibiotic treated mice, and the other non-antibiotic treated. In the antibacterial mouse model that was given antibiotics for 5 days, their blood glucose levels and lipid concentrations dropped significantly. When compared to the mouse model with the non-antibiotic treatment, the level still dropped but not as much. It was concluded therefore, that when the secondary bile is supplemented at the same time as antibiotics, blood glucose and blood triglyceride levels recovered and bounced back, suggesting that secondary bile acid produced by intestinal bacteria affected sugar and lipid metabolisms. Knowing this information gathered from this research shows that there is possible future research that could be done on these bacterial cells to bring researchers closers to finding a preventative or treatable way to treat metabolic diseases. In my opinion this is a grand discovery, the research conducted follows up with previous research done on the bacterial cells in the intestine, and now more information was able to be gathered to further knowledge in this area. I believe with just a further amount of research and patience, there is a very high chance the treatment to many common and popular metabolic diseases could be developed and found.


To read the research study conducted by the researchers at the Kumamoto University on Secondary Bile Acids: http://www.nature.com/articles/s41598-018-19545-1

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