In this study researchers have found that they can restore myelin formation and limb function in mice with MS with the microRNA miR-219. Multiple sclerosis is a disease that attacks the central nervous system. This disease destroys the myelin sheath and also oligodendrocytes. Patients with MS lack miR-219. Researchers deleted miR-219 in mouse models and found that several proteins that prevent myelin formation were present with the absence of the microRNA. Then they administered a synthetic version of miR-219 to the MS mice and found that myelin-producing cells were reactivated. This led to reformation of mylelin and improved limb function.
This could lead to a huge breakthrough in the treatment of MS for humans. MS is a horrible illness and millions of people in the world are affected by it. This disease could potentially be eliminated from the gene pool with more advances in medicine.
http://www.medicalnewstoday.com/articles/316599.php
http://www.cell.com/developmental-cell/fulltext/S1534-5807(17)30122-3
No comments:
Post a Comment