Some diseases, such as Huntington’s, sickle cell, and cystic fibrosis, are controlled by a single gene. These are called Mendelian diseases. This means that if a patient has a certain mutation on that one specific gene, that person will have the disease. However, in a recent study, researchers found a handful of people, who although they had the mutation, did not display any signs of the disease. This lead to the belief that understanding what makes these people different could help lead researchers to better treat, or even prevent, these Mendelian diseases.
In my opinion, the most interesting/exciting thing about this article is how researchers were able to utilize the genetic information complied by 23AndMe. This is just one of many articles I have read that mentioned they utilized 23AndMe. However, one big limitation to using 23AndMe, at least in this type of study, is that researchers cannot contact any of these individuals family members, so that prevents them from being able to compile an entire genome.