This is obviously a beneficial and successful step in genetics and developmental biology. I think it is ironic that humans have found a way to rectify a heritable disease dilemma in dogs that might not exist if it wasn’t for humans in the first place with the relentless need for purebred dogs. Nevertheless, I think this is a safe way to explore artificial selection and genetic enhancements without causing too much disruption. If this were humans, there would be outrage fueled be ye ole “designer baby, slippery slope” argument. In the case of dogs, we are just helping make our family friends a little healthier and happier.