Gene Involved in Lung cancer

According to the Science Daily,  researchers have been identified the gene that involved in the growth and spread of non-cell lung cancer tumors. Person who carries these non-cells lung cancers usually, they have mutation on epidermal growth factor receptor (EGFR) gene. Due to the mutation on epidermal growth factor receptor, it causes the spread and growth of tumor. Researchers studied families who had this cancer which showed that mutation on EGFR also cause the increased communication of the Fn14 gene. Researcher noticed that higher communication of the Fn14 gene develops lung tumor formation; however, if Fn14 gene subdue, it reduces the metastasis in non-cell lung cancer.

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Another article according to Southern Medical Center, researcher found same gene mutation on EGFR gene for lung cancer. These gene mutations are highly found in adenocarcinomas type of lung cancer where both smokers and non-smoker are affected. Highly amount of mutation on EGFR gene found on nonsmokers rather than smoker. Also, another KRAS gene involved which signal the pathways of the EGFR which common in males than females. Researchers said that two pathways were identified which distinguish that KRAS gene mutation affect smokers and EGFR mutation affect non-smokers. Now, researcher are trying to look for better treatment. This article is inserting to me because two different gene involve in lung cancer also those are affected equally rather person smoke or not, it doesn't matter.