Mahvash Disease Case Resolved With Liver Transplantation

By Tara Haelle

Mahvash Disease Case Resolved With Liver Transplantation | MedPage Today

GARD Rare Disease Information - Mahvash disease - National Organization for Rare Disorders (rarediseases.org)

Mahvash disease: an autosomal recessive hereditary pancreatic neuroendocrine tumor syndrome | International Journal of Endocrine Oncology (futuremedicine.com)

    Mahvash Disease is a rare genetic disorder of glucagon signaling characterized by pancreatic alpha-cell hyperplasia and hyperglucagonemia. This article talks about a 27-year-old woman getting a liver transplant who suffered from Mahvash disease which no treatment has been known to be found. Octreotide was used to decrease the glucagon levels. This showed how her getting a new liver wasn't a simple fix that would get her back to normal. I never heard of Mahvash Disease until reading this article. I felt bad that no cure was offered for this rare condition. I believe scientists haven't gotten to it because they tried to find a cure for major diseases like cancer. Mahvash disease only occurs in four cases per million individuals and only a dozen case reports have been found. This disease is known as an autosomal recessive disease which can occur in both males and females.