Selecting your baby’s gender may soon be a reality in light of a new sperm sorting technique. This new technique sorts sperm into a density gradient which will allow lighter sperm cells to float to the top of a container while heavier cells will sink to the bottom. Since sperm containing an X chromosome (female) are heavier and sperm containing a Y chromosome (Male) are lighter, it is now much easier to choose which sperm you want to fertilize the egg. Once implanted, the success rate is currently at about eighty percent for choosing the desired gender. This practice does have some genuine medical merit if a parent is trying to protect their child from having a disease that affects a certain gender in their family. To that end, I think this practice will create more widespread societal issues that are not being considered. This could easily lead to having a serious sex imbalance in our population and could lead to other modification techniques as the technology improves.
Showing posts with label gamete. Show all posts
Showing posts with label gamete. Show all posts
Friday, August 4, 2023
Tuesday, April 9, 2019
Obesity Leads to Gamete Damage
Obesity can lead to a multitude of
serious health problems. One that is not often discussed is the damage that it
can cause to sperm production. In one experiment Zucker rats, chosen for metabolic
characteristics that are close to our own, were examined for a variety of
traits revolving around reproductive function. Twelve rats were selected from
the same litter, some of which were over fed resulting in obesity. After being
examined it was found that obesity caused many problems in regard to
reproductive function.
Among
the things affected were the physical anatomy of the genitals, difference in
organ weight, onset of puberty, and sperm production. The affects obesity had
on sperm production were alarming. It was found that gamete production was
significantly decreased as well as having notable damage to the DNA. The DNA
fragmentation may result from cells that did not undergo apoptosis correctly
and proceed to spermiogenesis. This is most likely due to a deficiency in
leptin, a hormone that helps to regulate reproductive function.
These findings are startling to say
the least as these hormones and receptors are also part of our own genome. As the
obesity crisis continues on, we must start to worry about the damage being inadvertently
done to future generations. Not only do future generation have to deal with the
epigenetic effects of artificial additives and unknown consequences of GMO
foods, but they may very well be damaged before conception.
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