Showing posts with label Cancer Genome. Show all posts
Showing posts with label Cancer Genome. Show all posts

Friday, November 3, 2017

Scientist discover 27 genes that could halt cancer




       Once again, I decided to post about taking another positive step in the right direction to curing cancer. I know that we will eventually have a cure, it is just the journey of finding out more information about our cells in our bodies. The article that I chose was written by Honor Whiteman. It explains the brilliant study done by a few scientists at the Francis Crick Institute in the UK on suppressor genes in the body. 
     Human cells have two different copies of tumor suppressors. The difficulty of dealing with tumors in humans is that its extremely difficult to determine what suppressor copy isn't working. When a tumor forms, it means that both of these copies of suppressors aren't working properly. The scientist created a model that is able to study which suppressor genes are used when a tumor is present. They studied over two thousand tumors over a spectrum of twelve cancers.  The overall result of this study is that they were able to notice 96 gene deletions. What new information that was found was that 43 of these were suppressor genes are 27 were unknown. These new unknown genes will help fight tumors and cancers in humans. What they found will most defiantly help future medicines with suppressing different tumors or at least acknowledging what suppressor isn't working properly. 


Link: https://www.medicalnewstoday.com/articles/319943.php

Monday, November 16, 2015

Open Source For Cancerous Genome


Researchers from WuXi-NextCode, based in Shanghai, China, will sequence the genomes of 1000 cancer patients to identify new cancer-causing mutations and make the resulting database freely available to researchers.  The information could be used to develop new precision cancer treatment and make them available to people worldwide.  Doctors, cancer specialists and surgeons in San Antonio will help collaborate by gather tumor samples from patients with breast, lung, prostate, skin, colorectal, uterine, pancreatic, ovarian, stomach, brain cancer and blood sample with germline DNA, that does not carry mutation found in cancerous tissue.  NextCode is a spinoff from deCODE genetic based in Iceland where its technology was developed to handle analyzing and storing whole genome data from 350,000 people and validating more than 40 million variants.
This is interesting and could be useful for any of us who have plans to go into genetics or Oncology.  We could help find cures for cancer and NextCode would help with allowing everyone who uses it to share their findings and collaborate with each other.  I know that WuXi PharmaTech, the company that purchased deCODE for $65 Million in January, have a local lab in Philadelphia. I don’t think the local lab is part of this program but I do know they are constantly looking for scientist for their labs.


Tags: NextCode, deCODE, Cancer genome, open source sharing, WuXi PharmaTech