Monday, December 1, 2025

Genetic Link Found Between Sleep Patterns and Depression

Scientists have long known that sleep and circadian rhythms play a crucial role in human health, influencing metabolism, immunity, and cognitive performance. The article explains that many aspects of sleep such as duration, quality, and whether someone is naturally a morning or evening person, are moderately heritable, meaning genetics contributes significantly to these traits. Because of this, researchers are increasingly turning to genetic studies to uncover how specific DNA variations shape our sleep patterns and why disruptions in these biological rhythms can increase the risk of chronic diseases. The review highlights recent progress in identifying genes linked to sleep behavior and circadian timing, emphasizing how genetic research is helping clarify the biological foundations of sleep and its impact on overall health.

Link: https://www.nature.com/articles/s41576-022-00519-z

A large genetics study found that specific gene variations regulating sleep cycles are strongly linked to an individual’s risk for depression. People with a genetically “delayed” circadian rhythm are more likely to develop mental health disorders.
This study is important because it shows how our genes influence behaviors and emotions in ways we might not realize. Understanding these connections could improve mental health treatments and help personalize therapy based on genetic profiles.

Link: https://www.researchgate.net/figure/Genetic-Correlations-of-Depression-BIP-I-BIP-II-with-Biological-Rhythms-rggenetic_fig1_363736302



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