This latest mitochondrial editing approach is still quite a ways away from being used in clinics and hospitals. Researchers are currently using the technique in animal models similar to those of the human mitochondrial genome to test for any potential side effects. Since Ddda is easy to synthesize from bacteria, once the process becomes widely used in the medical field, price should not be too much of an issue. The potential prospects for the Ddda enzyme are promising and many scientists are looking towards Ddda to help cure genetic mitochondrial diseases in the future due to the precise modifications it allows scientists to make.
Article Link: https://www.nature.com/articles/d41586-020-02054-5
Related Link: https://pubmed.ncbi.nlm.nih.gov/15720251/