I believe that there are many ways that the severely ill Covid-19 patients could be in their position though a big one could be the immune defects and genetic effects. The reason I believe this is because the immune system helps fight off anything that can harm us. But if there is a genetic or immune defect, it could not function and let the virus is due to it not being able to fight the virus.
Sunday, September 27, 2020
Genetic or immune defects with covid-19
In "Genetic or immune defects may impair the ability to fight Covid-19," it brings in thinking of some reason of how. Many of the life-threatening cases were people who had genetic or even immune defects that caused them not to be able to fight Covid-19. The organization, Covid Human Genetic Effort, had brought up the fact that there are glitches in the severely ill-patients in type 1 interferon. Type one interferon is a molecule within the immune system that detects infection and stop it from continuing that does the same with viruses. In one, the severely ill patients have a mutation that makes it so they can't create the interferon. In the other, they found that the severely-ill Covid-19 patients had an antibody that connected to the interferon stoping its actions. In both cases, it causes severe effects on the patient due to genetic/immune defects.