Monday, October 7, 2019

Researchers Identify Second Short Sleep Gene



Scientists have discovered a second short sleep gene, which is a gene that promotes natural short sleep, meaning 4-6 hours of sleep every night for an individual but they wake up feeling completely rested.  The first gene was discovered in 2009 where researchers found that people who had a specific mutation in a gene called DEC2 got on average 6.25 hours of sleep every night but did not seem to have any negative effects from that short amount of sleep. 
Why Sleep Is Important For the Body - [Updated July 2018]


In the new study, researchers found another mutation in a gene called ADRB1 that was also linked with natural short sleep.  It was found that humans with the mutated gene slept on average about 2 hours less than humans with the normal gene.  Scientists performed experiments on mice with the mutated version of the gene.  The mice with the mutated gene slept 55 minutes less than the normal mice.  The ADRB1 gene was also shown at high levels in parts of the brain that are involved in subconscious activities.  They also found that normal ADRB1 neurons were more active during wakefulness and REM sleep and they found that the mutated ADRB1 neurons were more active than the normal neurons, which likely was a factor of short sleep.  I find it pretty interesting that genetics is the reason why some people can get 5 hours of sleep per night but still wake up completely refreshed the next morning.  Perhaps by conducting more studies on short sleepers, they could help people who don't have the mutated gene to find ways to still feel refreshed in the morning even without as much sleep. 

http://www.sci-news.com/genetics/second-short-sleep-gene-07559.html
https://www.cell.com/neuron/fulltext/S0896-6273(19)30652-X
https://ghr.nlm.nih.gov/gene/ADRB1

1 comment:

  1. Kylee,
    Your post is very similar to a blog I had posted regarding new studies searching for genes linked to the amount of sleep people tend to get every night. The gene that I concentrated on was the NSPR1 gene which is very similar to the ADRB1 gene you spoke about. This gene tends to make people feel fully rested when they roughly only got six hours of sleep. I hope they find a way to give people these genes that work in the medical field or the forces, this would help with the sleep deprivation these people face everyday in there line of work. Its weird that these genes were spoken about in a pair… Does that mean that one of our articles is a copycat of the other, or are researchers working on the same thing right now giving them different names?
    Thank you.
    -Jennifer Ortiz

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