A recent article published in the New York Times talks about how the genetic alphabet is getting a little bigger and it could
give us clues to how life in other parts in the universe could exist. For the
past 34 years Dr. Steven A. Benner has been trying to expand the alphabet of
DNA. Last month Dr. Benner and a group of scientist published a paper reporting
their success. The team of scientists not only expanded the DNA alphabet, they
doubled it. Successfully building an 8 base DNA as a posed to the regular four base
DNA. The 8 base DNA that consists of four natural and four unnatural bases and
crafting it was a marvelous feat. As they fit perfectly into the DNA’s double
helix and the enzymes can read them just as easily as natural bases. They named
their new system Hachimoji (hachi meaning eight in Japanese and moji meaning
letter.) Dr. Benner has started making unnatural proteins from these unnatural genes
and has started a company Synthorx to develop some of these proteins as cancer
drugs. On the other side of the spectrum scientists are heralding his work as making
huge strides in the computer science field as well. The Hachimoji DNA with its
8 bases is capable of holding much more information. One day rather than having
information embedded in silicon chips, it may just be encoded into a single
strand of DNA.
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