Our limited
understanding of how metastasis begins makes finding ways to stop it hugely
challenging. The article I chose discusses a new study that was done that may
provide more insight into this.
The researchers at the University
of California discovered how the surrounding environment of a tumor can cause
cancer cells to metastasize. To understand this, you first have to understand
how metastatic cancer occurs, which is when a cancer cell breaks away from a primary
tumor and moves to another area of the body usually but not limited to the
bones, liver, or the lungs. In their study, they built a 3-D collagen matrix,
which gave them the ability to get an in depth look at the migration activity
of various types of human cancers. By doing this the researchers found that a
condense environment caused the cancer cells to activate a distinct set of
genes, of a “gene module” which they later named collagen-induced network
phenotype.
This article captured my attention because
cancer is a huge thing in our world and it is taking many people’s lives.
Therefore, the better we understand these tumors and how they are
metastasizing, the better chance we have at finding a cure, or finding a better
road to recovery for those that suffer from it.
https://www.medicalnewstoday.com/articles/320141.php
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594574/
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