'It takes just a fraction of a second. You simply touch the chip to the wounded area, then remove it,' said lead investigator Dr Chandan Sen, director of the university's Center for Regenerative Medicine and Cell-Based Therapies.
'At that point, the cell reprogramming begin. "We reprogrammed their skin cells to become vascular cells,' Sen said. 'Within a week we began noticing the transformation.' Within a third week after this treatment, the mice's legs fully recovered.
The chip, loaded with specific genetic code or certain proteins, is placed on the skin, and a small electrical current creates channels in the tissue.
The DNA or RNA is injected into those channels where it takes root and begins to reprogram the cell. Because the technique uses a patient's own cells and does not depend on medication, researchers expect it to be approved for human trials within a year.