Is One Susceptible to Osteoarthritis?

Osteoarthritis, although the most common chronic musculoskeletal disorder, does not have enough information researched.

  

Susceptibility has been researched by the Laboratory for Bone and Joint Diseases in Japan. Osteoarthritis is a polygenic disease with a genetic component in which cartilage is progressively lost. Approximately fifty million people across the world are suffering from this disease. It causes pain and loss of joint function and there is no treatment. Among the genes found were ASPN, GDF5, and DWVA. Since I am interested in getting into Physical Therapy I am very intrigued with topic of osteoarthritis and the way the body can function after disease stricken. I believe finding the reason for osteoarthritis and being able to prevent it or even warn individuals would be wonderful for people struggling with the painful and at times debilitating disease.

http://www.nature.com/jhg/journal/v55/n2/full/jhg2009137a.html

https://www.ncbi.nlm.nih.gov/pubmed/21400473