Wednesday, March 8, 2017

Gene Mutations in brain-linked to OCD Behavior

Recent research have provided further evidence of how gene mutations can cause certain brain region to fuel behaviors associated with obsessive-compulsive disorder (OCD). The causes of OCD are still unclear, however, previous studies have suggested that the disorder could be due specific gene mutations. Northwestern University have pinpointed in their recent studies that gene mutations in the corticostriatal region of the brain is what's leading OCD-like behaviors on their test mice. The corticostriatal brain region is responsible for regulating repetitive behavior. The tests done in mice's brain have shown that there's synaptic receptors known as kainate receptors (KARs) that play a key role in the development of the region. By manipulating the KAR gene in mice's brain, it shows that it compels the mice to perform repetitive behavior. This could be a gateway to finding out why OCD occurs.
This is an interesting article since it was trying to figure out what a mental disorder like OCD is linked with genetics. The KAR gene mutation could effect the corticostriatal region of the brain in order to create the behavior.

1 comment:

  1. Mental disorders and behaviors always fascinate me, which drew me into reading your post and article. This is really interesting and makes me wonder if other mental disorders are derived in a similar way and if they could find a cure or treatment in the near future.