Thursday, December 8, 2016
Having A Bad Hair Day?
Prof. Regina Betz of Human Genetics at the University of Bonn in Germany published these findings in The American Journal of Human Genetics. Prof. Betz and her team gathered 11 children with UHS and sequenced their genomes. This data was then compared with large national databases to identify any UHS related mutations. The three genes that indicated mutations were located on PADI3, TGM3, and TCHH. The PADI3 gene influences the hair shaft protein. The TGM3 gene links hair shaft protein with the protein responsible for hair shape. The TCHH gene is responsible for the protein that maintains hair shape and overall structure with keratin filaments.
Looking further into this study, it was discovered that even if just one of these genes contains a mutation, there will be an abnormality in hair structure. This mutation also influences the hair structure of animals. Mice with any of the PADI3 and TGM3 gene mutations displayed fur abnormalities, as well.
As of now, there is no medical treatment for this condition because it is not seen as much of a medical condition. Hopefully, someday there will be some kind of remedy for people struggling with this daily issue.
Link To Full Article Here