Some people may be more likely to become obese than others. Some studies have suggested that heredity plays a part in weight. The World Health Organization claims that obesity is now the leading cause of illness in the US. The GAD2 gene, which is the glutamic acid decarboxylase gene, was one of the first to be found with association of obesity and eating behaviors in obese adults. However, they could not successfully repeat the study, so it is not truly known if this gene is involved. The GHSR, which is the growth hormone secretagogue receptor has been associated with common obesity and rare familial short stature/obesity syndrome. Epigenetics have also been looked at for a key factor in obesity. Prader-Willi and Angelman syndrome are due to variations in genomic imprinting at the proximal long arm of chromosome 15. Predisposition of obesity leads to other diseases associated with obesity, such as diabetes, cardiovascular issues, high cholesterol, and many more. Data also leads to the information suggesting that cultures who have ancestral history of poverty have been found to be obese. Many genes have also been studied that effect appetite.
Genes may very well play a major part in obesity. The kind of food that is available or affordable may also be a reason that certain areas are at higher risk of obesity and disease. I believe that most over weight individuals are a product of what they eat, mainly what is available for them to eat. But in some cases it may also be multiple genetic traits that lead to adult obesity.
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