Friday, March 13, 2015

First Study to Identify Genetic Links to Rosacea

Researchers from Stanford University and 23andMe conducted a study on the incurable skin disorder known as rosacea.  The researchers hoped that the study would help them understand the genetics of rosacea better.  22,000 23andMe customers volunteered to participate in the first part of the study.  2,600 volunteers reported that they had been diagnosed with rosacea.  The remaining 19,400 volunteers who were not affected by the skin disorder were used as controls.  29,000 23andMe customers consented to take part in the second part of the study in which the researchers validated the findings from the first part of the study.  3,000 volunteers were affected by rosacea.  The remaining 26,000 volunteers were used as controls.
            The scientists were able to identify two genetic variants (single nucleotide polymorphisms) associated with the skin disorder.  After collecting skin biopsies from six of the volunteers affected by rosacea, the scientists discovered that the genetic variants found were in or near genes that are associated with diseases such as diabetes and celiac disease.

            I found this study fascinating.  I think this study was successful in helping scientists better understand the genetics of rosacea.  I think it opened possibilities for future studies in which scientists will make an effort to further understand the two genes that were found to be associated with rosacea, diabetes, and celiac disease.

1 comment:

  1. Very interesting article! I also have rosacea and had no idea it was gene related or even associated with diabetes and celiac disease. I wonder if people with rosacea have a higher risk for these diseases and if so, doctors should require those diagnosed with rosacea to be tested for those specific diseases as well. Definitely an eye opener!

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