Clues to Disease Causing Genes

The New York Times recently published an article titled "In Iceland's DNA, New Clues to Disease Causing Genes."  The article discusses how a research team from Iceland has decoded over 2,500 genomes, which can then be applied to other individuals genomes.  When comparing data, researchers were able to track the presence of certain mutations and compare the mutations to different diseases.  By doing this, they were able to state that certain mutations may encourage certain diseases to affect the individual.

Researchers looked at a variety of different genes and linked the mutations to certain illnesses (for example, MYL4 and atrial fibrillation).  Having the knowledge of mutations that lead to certain outcomes can make a new area of drug treatment.  There would not only be early prevention, but researchers could try to create medications to alleviate these diseases.  

Researchers also found a really cool and interesting mutation that regulates thyroid hormone production.  Depending on which parent the individual inherited it from, production will either be higher or lower.  

I think that it's really interesting that such a large genome is being built, and its not just to look at traits.  Studying the linkage of mutations and disease provides so much data for pharmaceutical development, and can even encourage people to take preventative measures.  Saying someone needs to eat better or do something because they have mutations that link to certain diseases is much more effective than saying there's a chance.  Overall, this is really neat and I hope something like this makes it over to the US.

Link 2: http://www.nature.com/ng/focus/icelanders/index.html