Breast cancer detection has become much more advanced than ever before. We are at the point where we are able to detect women who are at high risk for getting breast cancer. We also are able to determine whether a tumor removal is necessary or to continue chemotherapy. The genetics of breast cancers is still a bit of a mystery. The director of the Program Epigenetics and Cancer Biology (PEBC) at Bellvitge Biomedical Research Instiute (IDIBELL), Professor of Genetics at the University of Barcelona and ICREA researcher, Manel Esteller, have found the epigenetic patterns of breast cancer as well as its clinical consequences. They had studied 500 breast cancer tumors for the chemical signal methylation to compare to each other. They had found two subgroups within the breast tumors through epigenome. The first one is Epi-Basal, the characteristic is the loss of epigenetic markers causes the breakdown of chromosomes. The second is Epi-Luminal B, its characteristic is is epigenetic inactivation of genes that are suppose to protect against cancer.
http://www.sciencedaily.com/releases/2014/12/141210114314.htm
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