Genetic Testing for Gastric Dilatation-Volvulus

"Bloat" is one of the most common ailments affecting large-dog breeds.  This common unassuming misnomer refers to a serious life threatening condition known as Gastric Dilatation-Volvulus or GDV.  A dog suffering from GDV experiences a twisting of the stomach, which causes the organ to swell. The dogs natural reaction is to "retch and swallow air" leading to inflation of the stomach.  The trapped air causes a build up of pressure in the organ.  This excess of pressure quickly cuts off circulation greatly reducing, if not stopping blood flow from the caudal and abdominal end of the animal returning to the heart.  Most dogs with GDV die from shock if not taken immediately for emergency major surgery.
      

Veterinarian researchers Claire Sharp and Elizabeth Rozanski were awarded a two-year grant to begin genetic studies of GDV.  As of now it seems that the condition runs in the family but the exact mode of inheritance is unknown.  Researchers suspect the ailment is caused by a combination of environmental and genetic factors.  Sharp and Rozanski are looking to genetics to determine the cause and therefore a method of measuring risk for "bloat."  By creating a genetic test for the condition, dog owners could be pro-active about testing for and preventing GDV.  Furthermore,  it would also be an aid to dog-breeders to hopefully reduce the number of offspring with a predisposition to the condition.

      
Article: http://www.laboratoryequipment.com/news/2014/11/research-aims-id-genetics-deadly-dog-disease