Tuesday, April 8, 2014

Cancerous Zombie Cells Eat Themselves in Order to Stay Alive

Autophagy means "to eat oneself".  Autophagy is a process of cellular recycling where cell organelles called "autophagosomes" encapsulate extra or dangerous material and transport it to the cell's lysosomes to be disposed.  Autophagy breaks down unneeded cellular components into building blocks of energy or proteins to be used in times when needed in order to survive or to stay safe from poisons and pathogens.  In this article, a University of Colorado Cancer Center study team realized that if this mechanism stopped working, the cancer cells may be able to save them selves from death inflicted from chemotherapies.  This finding has a big effect on cancer research.  First, it shows a mechanism where autophagy controls cell death.  Second, it reinforces the clinical possibility of restraining autophagy to sensitize cancer cells to chemotherapies. 

With this new discovery, hopefully now researchers can discover patients that could benefit from drugs that work with this mechanism.  This could be a big breakthrough with cancer research and could help save millions of people in years to come.



Original article: http://www.sciencedaily.com/releases/2014/04/140405233847.htm
To learn more about Autophagy, visit: http://mct.aacrjournals.org/content/10/9/1533.full

3 comments:

  1. So I read the title and I thought you found some way to make zombies. But this article is cool since it talks about how cancer cells show a process where autophagy controls cell death and they reinforce the clinical possibility of restraining autophagy. I too believe this will lead to a new cancer treatment.

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  2. This is a great discovery. Hopefully this discovery can help scientists find more cures for patients with cancer.

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  3. It's still in my opinion that there are cures to cancers that the government are holding back on releasing due to the huge loss of money that will be lost in the Health field with no more need for chemotherapy, radiation, etc. More particularly on the article, I find it great that steps are being made in the right direction of finding more cures.

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