Friday, April 25, 2014

Cancer stem cells linked to drug resistance

In a recent article, researchers at the University of California School of medicine have discovered a molecule called CD61 on the surface of drug resistant tumors that appear responsible for inducing tumor metastasis by enhancing the stem cells properties of cancer cells. In most cases, most drugs used to treat lung , breast and pancreatic cancer also promote drug-resistance and ultimately spur tumor growth. Based on these findings, Hatim Husain, MD and assistant professor who treats lung and brain cancer patients at Moores Cancer Center, has designed a clinical trial to attack the pathway of patients with drug resistant tumors. This will be, however, begin with patients who have lung cancer and have experience of cancer progression and drug resistance to erlotinib. This is expected to begin next year. Husain states that "based on the research findings, we hope to better understand and exploit the "Achillies heel" of the Drug-resistant tumors. I believe this research is a better understanding and a step forward to killing the cancer cells. This will take time however and were hoping that it becomes a success in trials.


original article: http://www.sciencedaily.com/releases/2014/04/140420131521.htm

secondary article: http://guardianlv.com/2014/04/stem-cells-increase-in-cancer-patients-possibly-from-drug-resistance/





2 comments:

  1. I've done a small research paper on certain areas of stem cell research, so this post seemed to be one that would interest me. The doors that stem cells are opening will really change the world as we know it. People who need transplants can now look elsewhere and now cancer is now being effected. This road can only lead to good things and I am happy we are taking it.

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  2. It's pretty unbelievable how far science has come in the treatment of diseases in illnesses. To begin fighting cancerous tumors is a great thing and will really impact our society. To find this supposed "achilles-heel" to drug-resistant tumors will prove a difficult task but if this team can even find small window of opportunity it will prove beneficial. This could give change to how we treat and fight cancers in the future.

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