Thursday, April 11, 2013

Research finds role for gene silencing protein





The article talks about how important it is to pay attention to the tail end of a gene as well as the front. They talk about the dicer-like 4 and how it helps go in and clean up and form the gene product and produces tiny RNA's in cells.   Scientists at the John Innes Centre on Norwich Research Park found that DICER-LIKE 4 steps in when effective termination through normal mechanisms has not occured.  DCL 4 plays a role in transcription termination and gene silencing.  When termination fails DCL 4 is a great back up for gene expression and gene silencing. 

To article: http://www.sciencedaily.com/releases/2012/03/120329141923.htm

Research on Dicer protein:

http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028548

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