Monday, November 12, 2012

The role of Genetics in Eating Disorders

Concentric circles complicate predisposition of eating disorders
This article uses family, twin, and molecular genetic studies which support the hypothesis that, there is a large influence of genetic inheritance and predisposition for eating disorders. For many years, it was thought that eating disorders were strictly a social choice; today, it is classified by the DSM 4 as an Axis 1 disorder. There is much research regarding the heritability of eating disorders regarding the existence of an altered serotonin neurotransmitter specifically in Anorexia Nervosa. There is also a co-morbidity factor between those with Anorexia Nervosa and anxiety, depression, obsessive compulsive disorder and other anxiety disorders while Bulimia Nervosa was linked more with substance abuse, bipolar, and other mood disorders. The problem with studying eating disorders in general in the nature versus nurture issue. Bulimia and Anorexia can both be associated with other mood disorders that are known to be caused by distorted levels of certain neurotransmitters. These altered levels are often seen in many mood disorders and other addictions. The same transmitters are affected. How much does the environment influence the development of an eating and how much, if any is caused by genetics?

A very interesting study was conducted in 2004 by a woman named Ann Becker. She introduced American television to the people of Fiji in the 90's. Before the introduction, women in general were very happy with there bodies and had no reason to be unhappy. After the introduction, the incidences of dissatisfaction and dieting increased dramatically. This proses a question about how much environmental influence has on ones own insight into their own views of themselves.

 


1 comment:

  1. [...] Helping gene therapy, which is right? 25. Which of the following statements is most suitable for tr...herapy gene? A. A dominant mutation (as in Huntington's disease). b. A recessive mutation (as in cystic fibrosis). C. An extra chromosome (as in the Down syndrome). D. Gene amplification (as neu in breast cancer). E. A chromosomal translocation (as in Burkitt's lymphoma). The answer is B. Need know why A, C, D and E are not correct. Thank you! Gene therapy is based on the concept of adding a gene that is lacking or deficient in function in a particular patient. A does not work because Huntington's disease is dominant. By definition, the dominant mutation "overcome" any allele associated with the same allele. Therefore, the allele must be removed or eliminated. " C is incorrect because the syndrome is caused by an extra chromosome 21. At this point, it is impossible delete an entire chromosome in any cell or denied because their activities together. I'm not familiar with D. E is similar to C. It has an area of large-scale DNA to be addressed to maintain silence. At that time the technique can handle only a few genes at best. Genes and the Microenvironment: Two Faces of Breast Cancer [...]

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