Proteins Capable of Evoking Breast Cancer Development

According to ScienceDaily, two proteins have been linked to the progression of breast cancer. The two proteins that were linked are JMJD2C and HIF-1. Breast cancer cells have the ability to use partnered proteins to unlock cancerous genes. The JMJD2C protein has the ability to release harmful genes that result in the growth of tumors. The HIF-1 protein has the ability to turn on genes, but can also be controlled by a cancer influencing variable which can result in an increased malignancy in breast tumors. On a positive note, the majority of genes that can be activated by HIF-1 are enclosed within mature cells, and cannot be unlocked without the JMJD2C partner. When HIF-1 and its partner JMJD2C are readily available to one another the HIF-1 protein turns on the JMJD2C gene and initiates protein production, which in turn activates the target genes. If the JMJD2C protein is unavailable when breast cancer cells are present then the tumor cells will be less likely to evolve.

This article was interesting because of the detailed information that it provided on cancer and how proteins can be a significant influence towards cancerous genes. The information provided in this article provides hope for a potential target in relation to cancer drug development.