The Polymerase Chain Reaction is cyclical in nature and closely related to temperature. When exposed to high temperatures the DNA-copying reaction resets and when exposed to lower temperatures a new set of reactions can begin. The actual proteins catalyzing these reactions are very fast, but the heating and cooling of metal blocks by machines known as thermocyclers takes some time for each cycle. These researchers from the Lawrence Livermore National Laboratory combatted this with their new device. This has two reservoirs of water with one kept at a high temperature and the other kept at a low temperature. When needed the water is pumped through a foamed copper block that is holding the sample, which lowers the heating and cooling times dramatically. There is some loss in efficiency with these faster speeds, but if the time is raised to a little under five minutes, from the fastest speed of two minutes and eighteen seconds, the efficiency can be improved. The results still need to be assayed, but the entire process may be able to be completed in about an hour.
I believe this could be very useful in a medical setting as results can be returned and treatment can begin much more quickly than ever before. This could help patients who have certain diseases where every second counts and improve their chances of becoming healthy.
I am so excited for this piece of technology. Maybe in the future hospitals and other medical facilities will have one of these on site and patients will be able to get their results the same day they get sampled. When more people use this technology, the cost will go down, and more people will have access to it. It's amazing how quickly medical technology has advanced these days.
ReplyDeleteIt is amazing to see how the advancement of technology has made such a difference in the medical world. Cutting down the time by hours could make a huge difference and give us the information we need to make better decisions and be able to learn more about whats going on.
ReplyDelete