An article in Medical News Today, called Genetics of Hypertension, is about a recent discovery of the functions of messenger RNA (mRNA), microRNA (miRNA), and renin in the kidneys. The article tells about how they affect one another, causing hypertension of the blood.Blood Pressure is defined as the force of the blood pushing against blood vessel walls. High blood pressure, or hypertension, is dangerous because it constricts the walls of the blood vessels, causing the heart to work harder to pump blood throughout the body.
The exact causes of high blood pressure are unknown, although scientists have been aware that kidneys play a role in blood pressure regulation. This is the first time that scientists have been able to identify specific genes that contribute to the process and also found miRNAs that control the expression of the hormone renin.
The findings were discovered during a gene expression analysis of the human kidneys. Researchers examined kidney tissue samples from 15 hypertensive males and 7 males with normal blood pressure and various techniques were used to study the mRNA and miRNA in the medulla and the cortex of the kidney.
Researchers commented on the findings saying that it is the first real evidence to implicate that the hormone renin is a cause of high blood pressure. The study also showed, specifically, which genes and miRNA produce renin. The results of this research has the potential to pave the way for new hypertension therapies and medicine.
No comments:
Post a Comment