According to Kathleen McAuliffe and Discovery Magazine, J. Craig Venter, as part of the Minimal Genome Project, synthesized a modified version of the one million base pair M. mycoides genome and implanted it into a DNA-free bacterial shell of Mycoplasma capricolum. It was shown to be self-replicating. He accomplished this daunting task by synthesizing the entire genome of the bacterium Mycoplasma mycoides, which infects goats and cattle, through the Utilization of computers and a forty million dollar budget. Venter used chemicals to fabricate the genome and tagging it with a blue indicator, transplanted it into an emptied out, closely related bacterium cell. After many attempts, over the course of a few days, the bacterium morphed into a blue bacterium with the characteristics of the implanted DNA.
Saturday, November 19, 2011
A Synthetic Organism?
According to Kathleen McAuliffe and Discovery Magazine, J. Craig Venter, as part of the Minimal Genome Project, synthesized a modified version of the one million base pair M. mycoides genome and implanted it into a DNA-free bacterial shell of Mycoplasma capricolum. It was shown to be self-replicating. He accomplished this daunting task by synthesizing the entire genome of the bacterium Mycoplasma mycoides, which infects goats and cattle, through the Utilization of computers and a forty million dollar budget. Venter used chemicals to fabricate the genome and tagging it with a blue indicator, transplanted it into an emptied out, closely related bacterium cell. After many attempts, over the course of a few days, the bacterium morphed into a blue bacterium with the characteristics of the implanted DNA.
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This is cool because it shows how far we are being able to come and what we are able to do with genetic engineering. This seems like it could be a pretty big step, to be able to synthesize an organism. (You would just need to find a spare 40 million dollar budget, haha)
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