New Gene Therapy Technique On Induced Pluripotent Stem Cells Holds Promise In Treating Immune System Disease

Researcher have develop a new technique to treat chronic granulomatous disease (CGD), according to study published in Blood, the Journal of the American Society of Hematology. this technique uses gene therapy on stem cells to correct chronic granulomatous disease (CGD) in cell culture, which could eventually serve as a treatment for this rare, inherited immune disorder. CGD prevents neutrophils, a type of white blood cell of the immune system, from making hydrogen peroxide, an essential defense against life-threatening bacterial and fungal infections. Most cases of CGD are a result of a mutation on the X chromosome, a type of CGD that is called "X-linked" (X-CGD).