A team of scientists led byDr. Alex Deiters and Dr. Jeffery Yoderv did research to find a way to control a genetic off switch in a way to be activated by UV light. They developed a way to turn genes off at a specific time and specific region of an organism. Both doctors had seperate teams. Dieter team came up with a way to synthesize morpholinos that would only bind with RNA molecules after brief exposure to UV light. Yoderv's team tested the caged morpholinos confirming the morpholinos did not disrupt gene function. They were successful in their research by caging morpholino and then using a uv light and by doing this they effectively controlled a genetic off switch. The article is interesting because who would ever think you can control a genetic off switch. I have an article attached on how genetic switches work that goes along with this article.
To article:
http://www.sciencedaily.com/releases/2010/10/101028121108.htm
To another article:
http://www.ncbi.nlm.nih.gov/books/NBK26872/
