Showing posts with label APA. Show all posts
Showing posts with label APA. Show all posts

Friday, February 28, 2014

Advancing Paternal Age

older-dad

         Studies at the University of Indiana have shown that there may be a connection between the age of the father during conception and the risk of the child having autism, schizophrenia, and/or learning disabilities. Advancing Paternal Age, or APA, has been perceived as a risk to a child’s health because of the increased likelihood of ‘de novo’ mutations. ‘De novo’ mutations are mutations specifically introduced into a family by a parent for the first time in the hereditary line. The University did a study on several Swedish children over a 28 year period. The study involved many children with siblings from the same father, (one born in the fathers twenties, and the other in the forties) to conclude whether the age of the father had a large impact on the child’s risk of autism, schizophrenia, and intellectual problems. The study concluded that the children born to older fathers had a higher risk, but several variables were not taken into account such as if the children were raised in the same manner or with the same mother. Even with these variables, the University believes their results are reliable evidence. Read more about the consequences of late parenthood here. 
          This article proved to be scary to me personally. My four year old sister’s father, my step-father, was forty four when my sister was born. Although my sister is a perfectly healthy little girl, the risk was still terrifying. I believe parents should be very careful in planning when to have their children.