Thursday, March 19, 2026

A Pattern of Hair Loss in Genetics

  Many people believe that baldness was originally caused by their mentally health and diet, this is correct; However, in reality, genetics also contribute significantly to the risk of hair loss.

    The article explains Androgenetic alopecia (AGA), also known as pattern baldness, is one of the most common genetic conditions affecting both men and women. Researchers at the National Institute of Health show that hair loss is not caused by just one gene. Instead, multiple genes work together to influence if someone experiences hair thinning or baldness. One of the most important genes involved is the androgen receptor (AR) gene. This gene affects how hair follicles respond to hormones like dihydrotestosterone (DHT). In people with certain genetic variations, hair follicles become more sensitive to DHT, which causes them to shrink over time. Consequently, hair becomes thinner and eventually stops growing.

   Although AGA is inherited from both parents, estimating shows men have a higher tendency of hair loss (85%) compared to women (33%).


    Besides genes creating the risk, this study highlights lifestyle factors as high level of stress, poor diet, lack of sleep, low exercise and overall health can also influence how quickly hair loss happens. However, even if someone has the genes, it "does not always" mean they will definitely go bald.


    Today, treatments including oral minoxidil, finasteride and low-level laser therapy have been discovered and implemented successfully. It has partially helped people with AGA improve their appearance, thereby enhancing their quality of life. This article helps scientists better understand the genetic causes of AGA and may lead to earlier risk prediction, also more effective treatments in the future.


Source:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12837269/

Another Source:
https://medlineplus.gov/genetics/condition/androgenetic-alopecia/

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