Are Genetically Modified Pigs the future of Organ Transplantation?
Imagine needing a life-saving organ, and there aren't enough donors to get it. Now, picture receiving that organ from a Pig. Sounds Crazy, Right?. Well, it's not that wild, scientists are already making this happen. Now, in the U.S. there are more than 100,000 people waiting to receive an organ, so researchers are looking to genetically modified pigs as a potential solution. So far, there are two biotech companies, Revivicor and eGenesis which are cloning pigs with modified genes to make their organs more compatible with humans. These pigs are specially designed so their organs won't trigger the human immune rejection and recently, the FDA has approved these organs for clinical trials.
Monday, March 10, 2025
Are Genetically Modified Pigs the future of Organ Transplantation?
As of now, there have been six patients that have been transplanted with pig's organs. The first four patients were very ill, and showed mixed success, as three patients survived for few months, while one died after 3 months after transplantation, but it's kidney was removed after 1.5 months. However, the real hope came when these organs were transplanted into healthier patients, from which Tawana Looney who was transplanted with pig's kidney, was almost immediately transformed and has been living with a pig's kidney for past three months, and another patient Tim Andrews, who also received a pig's kidney is also doing incredibly well.
The idea of Xenotransplatation, (process of using non-human cells, tissues and organs, like pig kidneys, to treat human medical conditions) seems something from a movie, but it could actually save lives. There must be various ethical concerns, but the major risk I think is, getting infected with virus from pigs. But, if this works, this could be a game changer for people who are stuck on dialysis or waiting years for donor organs.
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